Vice-president to launch Sports Talent Portal on Aug 28

first_imgNew Delhi, Aug 26 (PTI) Vice President of India Venkaiah Naidu will officialy launch the Sports Ministrys much-awaited National Sports Talent Search Portal at the Indira Gandhi Indoor Stadiunm here on August 28. Sports Minister Vijay Goel said the Vice President has given his consent to be the chief guest of the ceremony. “There have always been issues regarding fair selection of talented sports personhs in the state, national and international levels for teams in various sporting disciplines in our country,” Goel said. “This has been a serious issue for our government and acordingly we took steps to evolve this portal, where every child who ys talented in a particular sport or his teacher of parent can upload the sporting achievements of the child who is eight years of age,” he said. Goel said this achievements will be considered by the Sports Ministry and Sports Authority of India while shortlisting the talented kids, who will then be called for trials at the nearest SAI Centre for final slection. The portal will provide a three step simple process for registration, pofile creatin and upload of achievements. Goel said around 1000 kids will be selected and they will receive scholarships of Rs 5 lakh per year for eight years. The portal will be available in English and otherv regional languages so that it is easier for any boy or girl who is talented in a particular sport to upload his or her achievements from any part of the country. The portal will also be avialable as as App which can be downleaded on smartphones. Besides, the Sports Minister today also announced the first edition of Rural Games or Grameen Khel Mahotsav which will start from the Capital. The first stage of the Rural Games will be held in Alipur, Mehrauli, Nangloi, Najafgarh and Shahadara from August 28 to September 1. PTI SSC AH AHadvertisementlast_img read more

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Scientists Build Nanostructures out of Single DNA Strands

first_img Explore further (PhysOrg.com) — With its unique double-helical structure, DNA has the ability to be used as a programmable building material to construct designer nanoscale architectures. Complex DNA architectures could have a variety of applications, from DNA-based nanomotors to biosensing and drug delivery. Taking the research a step forward, researchers have recently constructed a nanometer-sized tetrahedron from a single strand of DNA, using a method that could have advantages for assembling similar structures on a large scale. Front and top views of the 3D molecular model of the tetrahedron. Image copyright: Zhe Li, et al. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The researchers, from Arizona State University (ASU) and the Hong Kong University of Science and Technology (HKUST), have published their results in a recent issue of the Journal of the American Chemical Society. As the researchers explain, the variety of different artificial DNA constructions has been increasing. So far, 3D DNA nanostructures are made from multiple DNA strands (oligonucleotides) with deliberately designed sequences. In this new study, Hao Yan of ASU, Yongli Mi of HKUST, and their colleagues have shown that DNA tetrahedrons can now be self-folded from only a single DNA strand. In addition, they demonstrated a method to replicate the DNA tetrahedrons in vivo, which could also be applied to the design and replication of other DNA nanostructures in the future.“A self-folded 3D nanocage that can be replicated in vivo tells us how powerful nature’s machineries are,” Yan and Mi told PhysOrg.com. “DNA nanostructures can serve as scaffolds to organize other material with controlled spatial arrangement. Spatial dependent biomolecular/nanomaterial interactions can thus be tuned and studied.”The DNA tetrahedrons, made of four triangular faces, were constructed from a DNA strand that was 286 nucleotides long. The tetrahedron’s six edges were composed of double helices: five were identical (double helical), while the sixth edge had a more complex “twin double-helical” structure. Four of the edges contained a cleavable site in the center, and all four vertices consisted of an unpaired thymine base to allow adequate flexibility for folding at these corners. Once the DNA strand was paired in this way, the researchers annealed the DNA in a process of heating and then cooling. When annealed, the DNA strand self-assembled into the seven-nanometer-long tetrahedron shape by combining the appropriate base pairs together. After confirming the successful assembly of the DNA tetrahedron, the researchers then developed a method to replicate the nanostructures using in vivo cloning in order to produce the nanostructures on a large scale. The researchers inserted one of the tetrahedrons into a cloning molecule called a phagemid, and then recovered several replicated tetrahedrons through a process of restriction digestion of the phagemid. This method is fully scalable, with the yield of cloned structures proportional to the size of the culture medium. As the researchers explain, using only a single DNA strand for creating nanostructures has several advantages, including simplifying the assembly process, increasing yield, offering the ability to scale up production, and creating structures with longer life spans in biological systems, such as inside living cells. This property is especially appealing for in vivo applications such as biosensing and drug delivery. In the future, the researchers hope to build on this method to synthesize nanostructures out of RNA, as well as build other complex shapes.More information: Zhe Li, Bryan Wei, Jeanette Nangreave, Chenxiang Lin, Yan Liu, Yongli Mi, and Hao Yan. “A Replicable Tetrahedral Nanostructure Self-Assembled from a Single DNA Strand.” J. Am. Chem. Soc. Doi: 10.1021/ja903768fCopyright 2009 PhysOrg.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or part without the express written permission of PhysOrg.com. Citation: Scientists Build Nanostructures out of Single DNA Strands (2009, September 8) retrieved 18 August 2019 from https://phys.org/news/2009-09-scientists-nanostructures-dna-strands.html Using living cells as nanotechnology factorieslast_img read more

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